Cheolwoo Park
Department of Life Science ,Chosun University, Korea
Title: The Anti-Obesity Effect of Pinus densiflora Sieb. et Zucc. in mice
Biography
Biography: Cheolwoo Park
Abstract
Pinus densiflora Sieb. et Zucc. (red pine) have various biological activities and widely distributed around East Asian countries, including Korea, Japan, China, and southeastern Russia. Although P. densiflora has been used traditional medicines, scientific evidence of anti-obesity effect has not been reported. The aim of this study was to investigate whether pine needle extract powder (PNEP) decreased body weight and white fat mass in ICR mice. We designed four group that similar in weight : normal diet (ND), hight fat diet (HFD), PNEP (300mg/kg and 500mg/kg). Their body weights were monitored twice weekly during the feeding period on 12 weeks. In comparison with HFD mice, PNEP (500mg/kg) group showed significantly lower body weight gain (-23%), white fat mass gain (-71%). Also, Blood analysis results that total lipid, cholesterol, free fatty acid, triglyceride and ALT were significantly decreased in the PNEP (500mg/kg) group compared with that in the HFD group. We confirmed that PNEP were significantly decreased body fat, white fat mass and obesity blood factor through blood analysis in ICR mice. Therefore, PNEP can be considered for use in therapy to control body fat and to develope functional food.