Texas A&M University
The Wu Lab has expertise in metabolism and integrative physiology and nutrition. Currently, the research in Wu Lab is focused on elucidating roles of inflammation-metabolism interactions in overnutrition-associated insulin resistance, adipose tissue inflammation, and hepatic steatosis and liver inflammatory response. The Wu Lab is also interested in exploring roles of inflammatory and signaling molecules in regulating atherosclerosis, and in studying myeloid cell functions in metabolic diseases. Both cellular and integrative approaches are employed by the Wu Lab. In particular, the ongoing projects in the Wu Lab involve a number of mouse models in which gene(s) are over-expressed or disrupted in a cell-specific manner. The long-term goal of Dr. Wu’s research program is to elucidate the mechanisms underlying the pathogenesis of obesity and over nutrition-associated metabolic diseases including insulin resistance, diabetes, and fatty liver disease so that novel dietary and/or pharmacological approaches can be developed for preventing and/or treating metabolic diseases. Using molecular, cellular, and integrative approaches, the Wu lab is focused on investigating the interaction between metabolism and inflammation.
Obesity, insulin resistance, diabetes, and fatty liver disease.